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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '618bdf1e33f63995e43d32ea961130a12b99fe4c17ffe1831667f43cac7b5d09' 
  AND token = '5HAAvuzRFm/SDqtpMcz3bM3w/slBBsSkBTW7RKWHOig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}