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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1f8aedef590afde26ebd405e460f2143323e4e53e9535be6653d5c22acdec4eb' 
  AND token = '4gXAtF9SMKgRK1Br3g4zqQalx//7LnKaVG3n1deNjgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}