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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1a23d4bbd822402009b0b0bc98f5290894f347025dc8791a971369f82cd42408' 
  AND token = 'E9Mcj33f8qMYiqEvZAZR6EBE0N3SCDEh2ce9SzyPtYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}