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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a45e9fa05445a0cb86ee7e47261b9aadb89dd75b62823ff5e9703620467bf44b' 
  AND token = 'uC22Fjzm95sOJekRN+qkOV++39CWIo58nUw9LNOAHAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}