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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b10a226a87d020cec65b037ff890d8d5fbbe3b3beaa8281d8a7a377e1589f45e' 
  AND token = 'hbXM30KPYiklNXBIbC/We/jlpAjp3w8jmvhyTAZlbhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}