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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9fadbb4e4e71cf828ff7b974512ee03cd202154e444081ca09a3461de3701a69' 
  AND token = 'qGem2LP8/CzqYxMQt7uYepM8U4Df+dpxAa2zxhrJMw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}