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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1da694621feebf3cdf888e540d9163ea0a5eb9df64aa21e65d11c3e719ded07f' 
  AND token = 'lRlQlVB1kSPdC/yAhPiW2DEfS5kjQNPBlyCLK72LO3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}