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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '18e73dd82857dcffc122cf4ab36926cd3ae33d60e02e39306b5add45efaaa75f' 
  AND token = 'pwdDAnV/M2EzA6vLc4tLvCEW2z10d+5swUZZ7FF00Rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}