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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4e4575fecec944702d73734bab19a35ead4712c5ccfe1b0b0c4a22bc83f2dd1d' 
  AND token = 'M/DfMNNlAwAVukYwf1lXbuumFgfEEj1iFad+rI8CoiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}