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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ab5c3f1afa79847d5c165fba88c2a661ca0a40301762f79b5e03e29770a9b049' 
  AND token = 'uteP1M4P/MR56jxpVjpR/IP2p4fCczIYhq+k0Ve3p50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}