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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '500d15cb9b25c0c1ee2a03a4d5e27490b2433dea31bb81881795c4a90a28eeaf' 
  AND token = 'TaPfM0w4QCNfXWZ5cZ3I9cWddgrYlR6HYwUMVNMsYWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}