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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1e4820a22d3389512db880c40f2bc43876a48110f8540aabfbbac8060e1a4415' 
  AND token = 'hSVuvLN85ygAxgzdkx3vom7V3eoGeQMw52DblGkl1h0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}