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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c1cbf488541a3af423116518e3981904e040c3ed1aceff09576f9907925bcef7' 
  AND token = '5WfVRNs2aSKP7pGCQGsDy7zk1zeKD1NfWp1sOm0GIfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}