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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6cc648a356db46291fe51750e32d939f0d2a1ffa141ee41689fe56ec3c039f24' 
  AND token = 'Jd2l6LFK4UwzkpWcvdq2usamsY7U6sU4NXMYlGpUgRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}