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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a98f5f9c5600a6c4da92436ed16b221d10bb135146bab9ccf460fa7f8fd06ec' 
  AND token = 'tMyQekSq0/5vV95p+aXy9gM4wnaJtiOtCLv0hOu7kKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}