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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b4cf46e34dc663571efd089f8d4c2e64dbc99ea7fb302631e1de0598e1c19e99' 
  AND token = 'lyeUdmU3MTBdWmkl8MdofLN/IowIBGKw1lfNry8RFaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}