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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '754542b90e1bd9fcc111f2db5535ba756bec96c55eb050b78d6aecf6493fa17c' 
  AND token = 'ns5/4tXmSLztfhN42EjspS+MqL863VFG95fGyAQKiaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}