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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6398936fc096ef0cb746bbd301ecb099841d4a1282c466e43c7259f5df638c4d' 
  AND token = 'xBI80xuc16w8lnW5WhdnVfkryMHkyROmczSzRBXqcOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}