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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6b8cd1177994a6a7cab3203e15d4c69b14bba07a21aa51646d3f71eabd1b02a5' 
  AND token = 'zIsRmA9E2MhPggHDzt/IfRfuA+b9JbRnN1r1cz1CmoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}