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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '45f218aa104a391b0ea7a4fd3423ce9e8339931c9aed3f6757aaf7356e836ed6' 
  AND token = 'Ns1tbrE1OoZu8no+Gdd0GxtvtZbTiJca2xPjexMxvQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}