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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9a148eec41c519d5f03ad5fdc164dd525c8b047f587f18f377f45c11c09d97b7' 
  AND token = 'FWtJ14/lUWj1PlGLOvSSVWev037TTRHUVzZp1zM9tUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}