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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5188748ba78efa2171b6359f1dbb3d69d3bc72ec8f57d17009e52a2e4daee544' 
  AND token = 'L53F0I0s8aBeWBqarruMY9JQ+YBbDvv8ritv4PoFOg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}