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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4ec7b5f1b78aa69b415b1fe583deebd568d4544b8d36e4c91592bc67b1d07ce9' 
  AND token = '2rTnqnoqHSkCDIniaYWrAB+FRDJVQ5MAG9lG2kFuzs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}