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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6c6f3ee9b64fa1952630e1642cdbe74b48823d42e688329bce62f0f82485ed79' 
  AND token = 'N9p3ZAXmktNT6j+Doq+LiLG4fTGxbx/ryEDNeaJstjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}