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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '246ef3209a48b8a7a1275e8ba52a7b4d0ab73708cc447934d6437437b237e4f1' 
  AND token = 'eeHlIdFMCFDBlaAyZ2DLLHbEkAKEEB+PLz9Z/r/mzWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}