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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c29017ee3e48c702c49eb018dcc6379f19d8cb94fd2f6d507349da238d6c7246' 
  AND token = 'ZXj9Yv5f6arfmczJekM5tYZAKVXvEi0VceU9ijOnRjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}