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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'deb1200b1571c61cacd6541f7dee58986b9e915aa3491f57fbc6b290538b817f' 
  AND token = '+sedzxLH7GKGIVXy6229uj5TMwGd61KbjHYxiD4DVA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}