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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '41e270f69f5c78029849962f723dce1b5c093321aa19e97c2aa306271c2a27a7' 
  AND token = 'fP07qwkZmYxc5yA4h4ZGIMPcnPgTjco21SpSHShmMnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}