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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '106d078a10138debf64627c5eef5189b6f866b35483852085abb46e5134fa4a5' 
  AND token = 'NGck1G5tzWF/xtFQSOdmKbWX8UjJrmJ9EdxfpGX4pUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}