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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '253e73707f34e2b0868fe482d0581cb93dd31fbf05e00aead52f38b84438573b' 
  AND token = 'l7/jthpt+QdT6aOeWskgQtZwcZZ13xL3J7rSJd+xv24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}