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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '165a8fa66613a604e77ef7feb096cdee8413ed604f96f5a35f6aa07494036020' 
  AND token = 'CUijbjLZN9lBsFZ60L3Y6w1mOOjsHu5wNg/BgWuNiHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}