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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7cb16aac2e8c9eed20e9b46d1ddb408df96c70a70a38a2e308d23f797c310133' 
  AND token = 'qPsrmm+NcChbOUg6qCL8UrpvnBz019JiWWOnNhLkIAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}