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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd260ee3ec642a04f75cd73420f85806525b60fb39a0ffc9f02b759a53252de96' 
  AND token = 'vUKOAoI23fczYD666D6CB8w7W2DscA7tWlZH35UliZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}