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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '069c165f379c9d5d4b726ed8b678295b828293ffece9bdec5bf1b11989aae283' 
  AND token = 'uhMtgR7GslQJe3LzHQ6R9MVF8tU0QUYQa6T9ZzEHWjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}