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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b0f82650fce34f67f0ec7b04aedcacdadb41867c830c06847f0694fa479f9c50' 
  AND token = 'npmGgDh6z1oOFJx++ikJHOGkP+WCpVxSGUmnEtoQ6yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}