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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '856be307242d0b8154cff07b7d2f95a095f4cee52110d5fa79f8c7852394886a' 
  AND token = 'EZOK0ofU5d6VV5RDMgNTERkCJkEBVNc5aCfR+3CbBNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}