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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ed3731c5aa045dcb7214d8bd403a8270271859f99e1c83990964a5ecdf3bdae6' 
  AND token = 'fj1E1g8M/W4f+WP6KAiHf4LemHql7dwLsDc/+yNna1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}