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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0ff79d41b1aae6fdb3d4d1586301c728b01db1ed40d0e95e4f33937338b9c743' 
  AND token = 'JXCLFTEvfU3EJZlSH2gs0U7R4uaiO0DNsHnUQGXj3AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}