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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0b294a517243152e4fcab00b4ff656085b87a4a225ce00815763f231f6cd6b1a' 
  AND token = 'YZS3SNqtml8NftTy0037E24iA4MX0hXjC7LCB4YX/wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}