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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '162834be92fbc4c002e6a190228c834980701099a65bb347203cfb0990091402' 
  AND token = '8mux/yqOeOJjhFaZ21TN2/JTeFS3NbsRZwLiEbb/MM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}