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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '64d9dc37fafbfcd19e9efd2539a7ec35ace6d9ce1cbde54a9e00eb1df49d410c' 
  AND token = 'PbDNzrETtqTmQvYvxNyy4UU6M6PJZRzM/Bi/KZCTmGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}