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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '38765554647517cb1468e11b16a7b18bfdc6de9bc50d8c8b1a71bdea9c505627' 
  AND token = 'hN29LYFPahStmG96k86OTDQZ3g+DbJ2k69snDdYyu9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}