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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a50ac438a68409fe87465f53fba7bf3f78c66af4410b161740f3efb95b5dc8d3' 
  AND token = 'oSYxKXo9f/OcRrhz9W0vy2QxetoM7MKo+zTeT19E4c8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}