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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '88130c86181afb390c41e0e5576acd894ebe0ec9ffd8bf6506ddd8caac4d8940' 
  AND token = 'Uzwd6d18I08/uc13DDaCNQdY72fCb2S34q1XzC9kIsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}