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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3882df706b93a0252341fb875e8e7d3c819f79bf5b7df05245488a4501c4d674' 
  AND token = '4USVmlLlKccK9m3lju/sB8AUiz4eq7kN2qACw8kKBNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}