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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c706fdbe6d215cef080e1ee8394290245ed8ae9049124c4f0a3d719e6c968e7a' 
  AND token = 'BN54NpZvKawm47GDWmxS4k/TeKC+fOzr5uCF2Gge5ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}