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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3fe058282b638ebefe5d93ecb0ebf4bbb2901d41f062e25e68dbf0da73a3c481' 
  AND token = 'eQwSmbh5q+Ddt98ANW8fZrX+Q4+Q+gve72ixqzRpERw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}