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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9c2cec52d804413e2115af57b8f70493146bab13079660d97fe94df54de9c815' 
  AND token = 'SPdiq4AEXbn6IPug36lo7vgLGbSSa3riePRjBz3k3E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}