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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cfdf60b0a3c6a6bd8bee11be1e4c30cee1f22306dbc71f0cb620da29a5f7f424' 
  AND token = 'pdTa2J/8npH4sXM9OTAsxSfp314KisxqWdhrpY4wt18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}