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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '48f53ea57e9af4fe5817c8e83e5e2b27d0ba9fbbccb495680ca7199e723e7c0d' 
  AND token = 'O205RIGXt6FKHcs7qwJRJ4i6XVRtWRqI2Iag1P6fxlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}